Endothelial Nitric Oxide Synthase Gene Is Positively Associated With Essential Hypertension

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Endothelial nitric oxide synthase gene is positively associated with essential hypertension.

Essential hypertension has a genetic basis. Accumulating evidence, including findings of elevation of arterial blood pressure in mice lacking the endothelial nitric oxide synthase (eNOS) gene, strongly suggests that alteration in NO metabolism is implicated in hypertension. There are, however, no reports indicating that polymorphism in the eNOS gene is associated with essential hypertension. We...

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the analysis of endothelial nitric oxide synthase gene polymorphism in intron 4 with hypertension disease

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ژورنال

عنوان ژورنال: Hypertension

سال: 1998

ISSN: 0194-911X,1524-4563

DOI: 10.1161/01.hyp.32.1.3